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Endothelial Underpinnings of Atherosclerosis

Last Name First Name Job Title COI Statement State Agarwal Amit 720CN-ASSOC PROFESSOR In Review Alger Jeffry 784VF-ADJUNCT PROFESSOR In Review Bailey Berkeley 3122-PSYCHOLOGICAL ASSOC II In Review Bailey Kenneth 730CN-ASSISTANT PROFESSOR In Review Baker Sarah Affiliated Individual In Review

The BRAIN lab, short for Brain Aging, Injury, and Modulation Lab, has two lines of research in the area of aging and neurodegenerative diseases.

Cotten-The role of intrinsically disordered linkers in defining the physical properties and spatial organization of biomolecular condensates

In addition to our work on mechanisms of FMRP function at synapses, we have also contributed to the understanding of circuit dysfunction in Fragile X Syndrome, with a goal to reveal mechanisms of FMRP function in the brain, but also to identify therapeutic targets to correct and restore circuit function

State-of-the-art sequencing facility that performs NGS coupled to bioinformatic analysis

At blood pH, UPSe nanoprobes were present as self-assembledmicelles with a diameter of 25.3± 1.5 nm and a spherical morphology (left panel, Fig. 2d). HomoFRET-induced fluorescence quenching was responsible for complete silencing of the fluorophores in the micelle state (Fig. 2c)24.

Synthesis of Kinase Inhibitors - Melanie Rodriguez Profile

At blood pH, UPSe nanoprobes were present as self-assembledmicelles with a diameter of 25.3± 1.5 nm and a spherical morphology (left panel, Fig. 2d). HomoFRET-induced fluorescence quenching was responsible for complete silencing of the fluorophores in the micelle state (Fig. 2c)24.

We study the impact of disease-related hypoxic stress with aging upon synaptic plasticity, white matter connectivity, and cognitive performance.